{"id":5758,"date":"2024-01-19T15:06:21","date_gmt":"2024-01-19T14:06:21","guid":{"rendered":"https:\/\/alpha1-deutschland.org\/?page_id=5758"},"modified":"2024-07-31T13:46:57","modified_gmt":"2024-07-31T11:46:57","slug":"test-alpha-1-antitrypsin-mangel","status":"publish","type":"page","link":"https:\/\/alpha1-deutschland.org\/en\/test-alpha-1-antitrypsin-mangel","title":{"rendered":"Test auf Alpha-1-Antitrypsin-Mangel"},"content":{"rendered":"<div id=\"fws_6a8e168c35e64\"  data-column-margin=\"default\" data-midnight=\"dark\"  class=\"wpb_row vc_row-fluid vc_row\"  style=\"padding-top: 0px; padding-bottom: 0px; \"><div class=\"row-bg-wrap\" data-bg-animation=\"none\" data-bg-animation-delay=\"\" data-bg-overlay=\"false\"><div class=\"inner-wrap row-bg-layer\" ><div class=\"row-bg viewport-desktop\"  style=\"\"><\/div><\/div><\/div><div class=\"row_col_wrap_12 col span_12 dark left\">\n\t<div  class=\"vc_col-sm-2 wpb_column column_container vc_column_container col no-extra-padding inherit_tablet inherit_phone\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n\n\t<div  class=\"vc_col-sm-8 wpb_column column_container vc_column_container col no-extra-padding inherit_tablet inherit_phone\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t\n<div class=\"wpb_text_column wpb_content_element\" >\n\t<p>For the<strong> \u201a&#039;Position paper of the DGP\/ <span class=\"fontstyle0\">Alpha-1-antitrypsin deficiency (AATM) <\/span><span class=\"fontstyle2\">\u2013 <\/span><span class=\"fontstyle0\">An expert statement&#039;\u2018 <\/span><\/strong><span class=\"fontstyle0\">is it okay <\/span><strong><span class=\"fontstyle0\"><a href=\"https:\/\/www.thieme-connect.com\/products\/ejournals\/abstract\/10.1055\/a-1143-8186\"><span style=\"color: #ff8000;\">here<\/span><\/a>.<\/span><\/strong><\/p>\n<p>Why test: <a href=\"https:\/\/alpha1-deutschland.org\/en\/kinder-jugendliche\/literatur\/\"><b>Unexplained transaminase elevation \u2013 have you considered alpha-1 antitrypsin deficiency?<\/b><\/a><\/p>\n<\/div>\n\n\n\n<div class=\"divider-wrap\" data-alignment=\"default\"><div style=\"height: 25px;\" class=\"divider\"><\/div><\/div>\n<div class=\"wpb_text_column wpb_content_element\" >\n\t<h1 class=\"vc_custom_heading\"><span style=\"color: #004267;\">Brief information on the test for alpha-1 antitrypsin deficiency\u00a0<\/span><\/h1>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"color: #ff6600;\">This information is intended exclusively for doctors.<\/span><\/strong><\/p>\n<p>\u201e&quot;If a reduced serum level is detected (&lt;0.9g\/l), molecular genetic analysis should then be initiated to detect various mutations in order to confirm the AAT deficiency by means of genotyping and\/or phenotyping and to be able to draw conclusions for an adapted therapy.&quot;\u201c<sup>1<\/sup><\/p>\n<p>\u201e&quot;It is important to know that alpha-1 antitrypsin is produced in increased amounts during infections. If the AAT level is measured during an infection, the value may therefore be falsely within the normal range, and a potentially existing AAT deficiency may be overlooked. Therefore, an inflammatory marker, such as C-reactive protein (CRP), is usually measured at the same time. If the CRP level is normal, an infection can be ruled out with a high degree of probability, and the AAT level is then meaningful.&quot;\u00b2<\/p>\n<p>The <a href=\"https:\/\/www.alpha-1-info.de\/de\/testverfahren\" target=\"_blank\" rel=\"noopener\">AlphaID<sup>\u00ae<\/sup><\/a>\u00a0genetic testing can be performed using a cheek swab. <a href=\"https:\/\/www.alpha-1-info.de\/de\/testverfahren\" target=\"_blank\" rel=\"noopener\">here<\/a> can be obtained free of charge (exclusively through the doctor).<\/p>\n<p><b>Registration is important.<\/b> the doctor&#039;s office and the sample.<br \/>\nBecause the information about the results of the AATM test with AlphaID<sup>\u00ae<\/sup>\u00a0This is done in an encrypted and web-based manner via the portal.\u00a0<span style=\"color: #ff8000;\"><a href=\"https:\/\/www.alphaid.de\/de\/login\" target=\"_blank\" rel=\"noopener\">www.AlphaID.de<\/a>.<\/span><\/p>\n<p>For questions about AlphaID<sup>\u00ae<\/sup> or its <a href=\"https:\/\/www.alpha-1-info.de\/de\/testverfahren\" target=\"_blank\" rel=\"noopener\">Application<\/a> Please contact the Grifols sales representative or, if you do not know who that is, contact the headquarters of Grifols Deutschland GmbH at Tel.: 069 \/ 660 593 100.<\/p>\n<p>&nbsp;<\/p>\n<p>1 Source: Alpha1-Antitrypsin Deficiency and Substitution Therapy \u2013 Current Developments and Clinical Significance, Prof. Dr. Andreas Rembert Koczulla<\/p>\n<p>\u00b2 Source: https:\/\/www.lungeninformationsdienst.de\/krankenen\/weitere-lungenkrankenen\/alpha-1-antitrypsin-lack\/diagnose<\/p>\n<\/div>\n\n\n\n\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n\n\t<div  class=\"vc_col-sm-2 wpb_column column_container vc_column_container col no-extra-padding inherit_tablet inherit_phone\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n\n\t<div  class=\"vc_col-sm-12 wpb_column column_container vc_column_container col no-extra-padding inherit_tablet inherit_phone\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n<\/div><\/div>\n\t\t<div id=\"fws_6a8e168c383b6\"  data-column-margin=\"default\" data-midnight=\"light\" data-top-percent=\"20%\" data-bottom-percent=\"20%\"  class=\"wpb_row vc_row-fluid vc_row full-width-section  top_padding_tablet_20pct top_padding_phone_20pct bottom_padding_tablet_20pct bottom_padding_phone_20pct\"  style=\"padding-top: calc(100vw * 0.20); padding-bottom: calc(100vw * 0.20); \"><div class=\"row-bg-wrap\" data-bg-animation=\"none\" data-bg-animation-delay=\"\" data-bg-overlay=\"false\"><div class=\"inner-wrap row-bg-layer\" ><div class=\"row-bg viewport-desktop\"  style=\"\"><\/div><\/div><\/div><div class=\"nectar-shape-divider-wrap\" style=\" height:80px;\"  data-height=\"80\" data-front=\"\" data-style=\"curve\" data-position=\"top\" ><svg class=\"nectar-shape-divider\" aria-hidden=\"true\" fill=\"#ffffff\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 1000 100\" preserveaspectratio=\"none\"> <path d=\"M 0 0 c 0 0 200 50 500 50 s 500 -50 500 -50 v 101 h -1000 v -100 z\"><\/path> <\/svg><\/div><div class=\"row_col_wrap_12 col span_12 light left\">\n\t<div  class=\"vc_col-sm-12 wpb_column column_container vc_column_container col no-extra-padding inherit_tablet inherit_phone\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t<div id=\"fws_6a8e168c38dab\" data-midnight=\"\" data-column-margin=\"default\" class=\"wpb_row vc_row-fluid vc_row inner_row  translate_y_-100px\"  style=\"\"><div class=\"row-bg-wrap\"> <div class=\"row-bg\" ><\/div> <\/div><div class=\"row_col_wrap_12_inner col span_12  left\">\n\t<div style=\" color: #ffffff;\" class=\"vc_col-sm-6 wpb_column column_container vc_column_container col child_column centered-text padding-6-percent inherit_tablet inherit_phone\" data-cfc=\"true\" data-using-bg=\"true\" data-shadow=\"medium_depth\" data-border-radius=\"15px\" data-padding-pos=\"all\" data-has-bg-color=\"true\" data-bg-color=\"#00899b\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" ><div class=\"column-bg-overlay-wrap column-bg-layer\" data-bg-animation=\"none\"><div class=\"column-bg-overlay\" style=\"opacity: 1; background-color: #00899b;\"><\/div><\/div>\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3 style=\"text-align: center\" class=\"vc_custom_heading vc_do_custom_heading\" >If you would like information material for your practice and\/or your patients, please send us an email to:<\/h3><a class=\"nectar-button large see-through-2\"  role=\"button\" style=\"margin-top: 30px; margin-bottom: 1px; border-color: #ffffff; color: #ffffff;\"  href=\"mailto:info@alpha1-deutschland.org\" data-color-override=\"#ffffff\"  data-hover-color-override=\"#ffffff\" data-hover-text-color-override=\"#000000\"><span>contact<\/span><\/a>\n\t\t<\/div> \n\t<\/div>\n\t<\/div> \n\n\t<div style=\" color: #ffffff;\" class=\"vc_col-sm-6 wpb_column column_container vc_column_container col child_column centered-text padding-6-percent inherit_tablet inherit_phone\" data-cfc=\"true\" data-using-bg=\"true\" data-shadow=\"medium_depth\" data-border-radius=\"10px\" data-padding-pos=\"all\" data-has-bg-color=\"true\" data-bg-color=\"#00899b\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" ><div class=\"column-bg-overlay-wrap column-bg-layer\" data-bg-animation=\"none\"><div class=\"column-bg-overlay\" style=\"opacity: 1; background-color: #00899b;\"><\/div><\/div>\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3 style=\"text-align: center\" class=\"vc_custom_heading vc_do_custom_heading\" >Further information from colleagues can be found at the Alpha1 Centers or by contacting our scientific advisory board.<\/h3><a class=\"nectar-button large see-through-2\"  role=\"button\" style=\"margin-top: 30px; margin-bottom: 1px; border-color: #ffffff; color: #ffffff;\" target=\"_blank\" href=\"https:\/\/www.alpha-1-center.org\/\" data-color-override=\"#ffffff\"  data-hover-color-override=\"#ffffff\" data-hover-text-color-override=\"#000000\"><span>Alpha1 Center<\/span><\/a><a class=\"nectar-button large see-through-2\"  role=\"button\" style=\"margin-top: 30px; margin-bottom: 1px; border-color: #ffffff; color: #ffffff;\" target=\"_blank\" href=\"\/en\/vorstand\/\" data-color-override=\"#ffffff\"  data-hover-color-override=\"#ffffff\" data-hover-text-color-override=\"#000000\"><span>Alpha1 Advisory Board<\/span><\/a>\n\t\t<\/div> \n\t<\/div>\n\t<\/div> \n<\/div><\/div>\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n<\/div><\/div>","protected":false},"excerpt":{"rendered":"Zum 'Positionspapier der DGP\/ Alpha-1-Antitrypsin-Mangel (AATM) \u2013 Ein Expertenstatement' geht es hier. Warum testen: Unklare Transaminasenerh\u00f6hung \u2013 schon an Alpha-1-Antitrypsin Mangel gedacht? Kurzinformation zum Test auf Alpha-1-Antitrypsin-Mangel\u00a0 &nbsp; Die Information...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5758","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Test auf Alpha-1-Antitrypsin-Mangel - Ihr Online Portal f\u00fcr Mitglieder und Interessierte<\/title>\n<meta name=\"description\" content=\"Exklusive Informationen zum Alpha-1-Antitrypsin-Mangel Testverfahren f\u00fcr \u00c4rzte und \u00c4rztinnen.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/alpha1-deutschland.org\/en\/test-alpha-1-antitrypsin-mangel\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Test auf Alpha-1-Antitrypsin-Mangel - 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