{"id":2306,"date":"2018-07-13T15:13:00","date_gmt":"2018-07-13T13:13:00","guid":{"rendered":"https:\/\/www.alpha1-deutschland.org\/?p=2306"},"modified":"2020-03-10T12:42:51","modified_gmt":"2020-03-10T11:42:51","slug":"mhh-presseinformation-transportsystem-fuer-spenderlungen-nach-mhh-studie-in-usa-zugelassen","status":"publish","type":"post","link":"https:\/\/alpha1-deutschland.org\/en\/mhh-presseinformation-transportsystem-fuer-spenderlungen-nach-mhh-studie-in-usa-zugelassen","title":{"rendered":"MHH Press Release: Transport system for donor lungs approved in the USA following MHH study"},"content":{"rendered":"<div id=\"fws_6a8dea68c0114\"  data-column-margin=\"default\" data-midnight=\"dark\" data-top-percent=\"3%\"  class=\"wpb_row vc_row-fluid vc_row full-width-section\"  style=\"padding-top: calc(100vw * 0.03); padding-bottom: 0px; \"><div class=\"row-bg-wrap\" data-bg-animation=\"none\" data-bg-animation-delay=\"\" data-bg-overlay=\"false\"><div class=\"inner-wrap row-bg-layer\" ><div class=\"row-bg viewport-desktop\"  style=\"\"><\/div><\/div><\/div><div class=\"row_col_wrap_12 col span_12 dark left\">\n\t<div  class=\"vc_col-sm-12 wpb_column column_container vc_column_container col no-extra-padding\"  data-padding-pos=\"all\" data-has-bg-color=\"false\" data-bg-color=\"\" data-bg-opacity=\"1\" data-animation=\"\" data-delay=\"0\" >\n\t\t<div class=\"vc_column-inner\" >\n\t\t\t<div class=\"wpb_wrapper\">\n\t\t\t\t\n<div class=\"wpb_text_column wpb_content_element\" >\n\t<h1><span style=\"color: #004267;\">MHH Press Release: Transport system for donor lungs approved in the USA following MHH study<\/span><\/h1>\n<\/div>\n\n\n\n<div class=\"divider-wrap\" data-alignment=\"default\"><div style=\"height: 50px;\" class=\"divider\"><\/div><\/div><div class=\"vc_separator wpb_content_element vc_separator_align_center vc_sep_width_100 vc_sep_border_width_5 vc_sep_pos_align_center vc_sep_color_grey wpb_content_element vc_separator-has-text\" ><span class=\"vc_sep_holder vc_sep_holder_l\"><span class=\"vc_sep_line\"><\/span><\/span><h4>Author<\/h4><span class=\"vc_sep_holder vc_sep_holder_r\"><span class=\"vc_sep_line\"><\/span><\/span>\n<\/div>\n<div class=\"wpb_text_column wpb_content_element\" >\n\t<p>MHH Press and Public Relations<br \/>\n<strong>Stefan Zorn<\/strong>, Director<\/p>\n<\/div>\n\n\n\n<div class=\"divider-wrap\" data-alignment=\"default\"><div style=\"margin-top: 25px; height: 5px; margin-bottom: 25px;\" data-width=\"100%\" data-animate=\"\" data-animation-delay=\"\" data-color=\"default\" class=\"divider-border\"><\/div><\/div>\n<div class=\"wpb_text_column wpb_content_element\" >\n\t<p>Transport system for donor lungs approved in the USA following MHH study; study on organ care system for the lungs successful \/ American Food and Drug Administration (FDA) grants approval \/ publication in Lancet Respiratory Medicine<\/p>\n<p>A large international research team led by physicians from Hannover Medical School (MHH) has demonstrated in the INSPIRE clinical trial that transporting and storing donor lungs in the Transmedics Organ Care System (OCS) is safe and effective compared to the current standard procedure of storing them at four degrees Celsius. Another clinical advantage: Patients who received an organ from the OCS experienced primary graft dysfunction less frequently, a common complication of refrigerated storage, which usually occurs within the first 72 hours. \u201cThis could mean that patients can be ventilated for a shorter time and discharged sooner,\u201d says Professor Dr. Gregor Warnecke, senior consultant at the MHH Clinic for Cardiac, Thoracic, Transplant and Vascular Surgery (HTTG) and principal investigator of the study. Twenty-one transplant centers participated in the international study, with MHH treating the largest group of patients. The physicians published their findings in the journal \u201cLancet Respiratory Medicine.\u201d.<\/p>\n<p>Based on the results of the study, the United States Food and Drug Administration (FDA) already granted approval for the OCS for storing lungs for transplantation at the end of March.<\/p>\n<h2><span style=\"color: #004267;\">Advantages of the Organ Care System<\/span><\/h2>\n<p>The OCS is a mobile device for ex vivo lung perfusion. Inside the device, the organ is transported at body temperature, perfused with a blood-like solution, and supplied with nutrients. The lungs are ventilated within the OCS, allowing them to oxygenate themselves. The device gives physicians up to twelve hours to transport the donor organ, assess lung function, and improve it: for example, by drying out fluid retention and suctioning mucus. &quot;This way, the organ reaches the recipient in a significantly better condition than with the previously standard cold storage,&quot; says Professor Warnecke. &quot;And the operations can also be planned more effectively \u2013 ultimately benefiting patient safety!&quot; Professor Dr. Axel Haverich, Director of the MHH Clinic for Cardiac, Thoracic, Transplant, and Vascular Surgery, adds: &quot;The number of organ donations in Germany is steadily declining. The OCS enables us to implant donor organs from more distant European countries here in Hanover \u2013 something that was previously impossible.&quot;\u201c<\/p>\n<p>The current standard method for transporting transplants at four degrees Celsius only gives transplant surgeons up to ten hours. During this time, the organ deteriorates continuously due to a lack of blood and nutrient supply, resulting in primary transplant dysfunction in up to 30 percent of patients after transplantation. This dysfunction leads to a decline in lung function and can ultimately be fatal.<\/p>\n<p>Various aspects of the research and development of ex vivo lung perfusion were supported by the three major transplantation research consortia of the MHH: the Cluster of Excellence REBIRTH (From Regenerative Biology to Reconstructive Therapy), the German Center for Lung Research (DZL) and the Integrated Research and Treatment Center for Transplantation (IFB-Tx).<br \/>\nFurther information can be obtained from the MHH press office, telephone (0511) 532-6772.<\/p>\n<p>A photo is attached. It shows Professor Dr. Axel Haverich, Director of the MHH Clinic for Cardiac, Thoracic, Transplant and Vascular Surgery, next to an OCS. You may use it free of charge in connection with this press release, provided you cite \u201cMHH\/Kaiser\u201d as the source and send us a copy.<\/p>\n<p>MHH Press and Public Relations<br \/>\nStefan Zorn, Head<br \/>\nTelephone: 0511 532-6772, Fax: 0511 532-3852,\u00a0<a href=\"mailto:pressestelle@mh-hannover.de\">pressestelle@mh-hannover.de<\/a>, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover. Further information from the MHH can be obtained at [website address missing].\u00a0<a href=\"http:\/\/www.mh-hannover.de\/\">www.mh-hannover.de<\/a><\/p>\n<\/div>\n\n\n\n\n\t\t\t<\/div> \n\t\t<\/div>\n\t<\/div> \n<\/div><\/div>","protected":false},"excerpt":{"rendered":"MHH Press Release: Transport System for Donor Lungs Approved in the USA Following MHH Study Author: Stefan Zorn, Head of MHH Press and Public Relations Transport System for Donor Lungs Approved in the USA Following MHH Study Study on Organ Care System...","protected":false},"author":1,"featured_media":3704,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,38],"tags":[],"class_list":["post-2306","post","type-post","status-publish","format-standard","has-post-thumbnail","category-allgemein","category-transplantation"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - 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